Publications

  1. K. Liu, J. Ottelé, S. Otto, Emergent Catalysis by Self-Replicating Molecules. In Supramolecular Catalysis (eds P.W. van Leeuwen and M. Raynal). 2021, doi:10.1002/9783527832033.ch41

  2. D. Komáromy, T. Tiemersma-Wegman, J. Kemmink, G. Portale, P. R. Adamski, A. Blokhuis, F. S. Aalbers, I. Marić, G. Monreal Santiago, J. Ottelé, A. Sood, V. Saggiomo, B. Liu, P. van der Meulen, S. Otto, Stoichiometry alone can steer supramolecular systems on complex free energy surfaces with high selectivity. Chem. 2021, doi:10.1016/j.chempr.2021.05.020

  3. B. Liu, M. A. Beatty, C. G. Pappas, K. Liu, J. Ottelé, S. Otto, Self-Sorting in Dynamic Combinatorial Libraries Leads to the Co-Existence of Foldamers and Self-Replicators. Angew. Chem. Int. Ed., 2021, doi:10.1002/anie.202101052

  4. C. G. Pappas, B. Liu, I. Marić, J. Ottelé, A. Kiani, M. L. van der Klok, P. R. Onck, S. Otto, Two Sides of the Same Coin: Emergence of Foldamers and Self-Replicators from Dynamic Combinatorial Libraries. J. Am. Chem. Soc., 2021, doi:10.1021/jacs.1c00788

  5. S. Yang, G. Schaeffer, E. Mattia, O. Markovitch, K. Liu, A. S. Hussain, J. Ottelé, A. Sood, S. Otto, Chemical Fueling Enables Molecular Complexification of Self-Replicators. Angew. Chem. Int. Ed., 2020, doi:10.1002/anie.202016196

  6. O. Markovitch, J. Ottelé, O. Veldman, S. Otto, Automated device for continuous stirring while sampling in liquid chromatography systems. Commun. Chem., 2020, doi:10.1038/s42004-020-00427-5

Behind the paper blogpost: https://go.nature.com/3qe2r3g

  1. S. Maity, J. Ottelé, G. M. Santiago, P. W. J. M. Frederix, P. Kroon, O. Markovitch, M. C. A. Stuart, S. J. Marrink, S. Otto, W. H. Roos, Caught in the Act: Mechanistic Insight into Supramolecular Polymerization-Driven Self-Replication from Real-Time Visualization. J. Am. Chem. Soc., 2020. doi:10.1021/jacs.0c02635

Highlighted in JACS spotlights.

  1. J. Ottelé, A. S. Hussain, C. Mayer, S. Otto, Chance emergence of catalytic activity and promiscuity in a self-replicator. Nat Catal, 2020. https://doi.org/10.1038/s41929-020-0463-8 (Preprint freely available on ChemRxiv: doi:10.26434/chemrxiv.10002032.v1)

Behind the paper blogpost: https://go.nature.com/2NHbTdi

Featured in :

News and views article in Nature Chemistry

Highlighted in c&en by Celia Henry Arnaud

Highlighted in phys.org

Dutch, Spanish and Russian media outlets

  1. B. Liu, C.G. Pappas, J. Ottelé, G. Schaeffer, C. Jurissek, P.F. Pieters, M. Altay, I. Maric, M.C.A. Stuart, S. Otto, Spontaneous Emergence of Self-Replicating Molecules Containing Nucleobases and Amino Acids, J. Am. Chem. Soc. 2020, doi:10.1021/jacs9b10796

  2. D. Komáromy, T. Tiemersma-Wegman, J. Kemmink, G. Portale, F. S. Aalbers, I. Maric, G.M. Santiago, J. Ottelé, A. Sood, V. Saggiomo, B. Liu, P. van der Meulen, S. Otto, Controlling Supramolecular Plasticity through Stoichometry, ChemRxiv, 2019, doi:10.26434/chemrxiv.10117343.v1